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HEALTH-ANGOLA:
Marburg Virus Death Toll Continues to Rise


Mario de Queiroz


-Marburg haemorrhagic fever has claimed 126 lives in Angola so far, but specialists fear this figure could rise dramatically in coming days.

LISBON, Mar 30 (IPS) -
This was the conclusion reached by the Portuguese experts participating in the fight to control the outbreak of the disease in the northern province of Uige, in this southwestern African nation with a population of 12 million and a total area of 1.4 million square kilometres.

According to a joint report from the Angolan Ministry of Health and the World Health Organisation (WHO), a total of 124 cases of Marburg infection were recorded between October and this past Monday, all in the province of Uige, and only five of the people affected had survived.

On Wednesday, however, updated figures raised the total number of cases to 127 and the death toll to 126.

On Mar. 17, the Portuguese government began sending medical supplies to help combat the outbreak of the devastating disease in its former colony, through the Portuguese Institute for Development Assistance (IPAD) and the Ministry of Foreign Affairs, in coordination with the Angolan authorities.

The supplies include fever-reducing drugs, disinfectants to treat the water, disposable gloves, masks and bedding, and 300 body bags.

There are no vaccines or medications to prevent or cure Marburg haemorrhagic fever, named after the German city where the virus that causes it was first identified in 1967. The earliest known cases were caused by contact with infected monkeys, which had been imported from Africa by a Marburg laboratory for scientific research.

It is still unknown how the disease is passed from monkeys to humans, but it can be spread from one person to another through bodily fluids like sweat, saliva or semen.

"Considering the dimensions of this hemorrhagic fever epidemic, there are plans for further aid shipments, in response to the requests of the Angolan Ministry of Health," said a press release issued Wednesday by the Portuguese Foreign Ministry, adding that this operation will continue for as long as necessary.

In Luanda, the capital, the Angolan authorities reported that the efforts to control the outbreak involve the Ministry of Health, IPAD, WHO, the U.S. Centres for Disease Control and Prevention, and the Belgian, Dutch, French and Spanish branches of the non-governmental organisation Médicins Sans Frontières, among other agencies.

The measures adopted include the active epidemiological monitoring of all people who have been in contact with Marburg fever patients, the training of medical and laboratory staff, and the coordination of social mobilisation activities, aimed at raising awareness on the disease in the community.

The treatment of patients is limited to keeping them in isolation, controlling their fever, attempting to keep their kidneys functioning and fighting haemorrhaging.

The Health Ministry/WHO joint report added that epidemiological surveillance teams have been established to detect potential cases in Luanda and Cabinda.

It also states that anyone who has been in contact with Marburg victims or the corpses of people who may have been infected with the virus should undergo medical observation for at least 21 days - the disease's incubation period.

The fear of a further spread of the virus has led the Angolan government to advise people who have been in the province of Uige in the last two weeks and suddenly develop a high fever or vomiting and diarrhoea to "seek immediate assistance at the nearest health care facility." They have also been asked to avoid travelling outside the country.

In Luanda, the Provincial Health Department announced Wednesday that it had set up an early warning system to detect suspected cases. Six telephone hotlines have been set up for calls from the public, as a means of gathering information on new infections as quickly as possible.

The worst Marburg epidemic recorded until now was in the Democratic Republic of Congo (formerly Zaire), where a total of 123 people died over the course of two years, between late 1998 and 2000.

Marburg fever is a rare, severe hemorrhagic fever caused by a member of the filovirus family, which also includes the four known species of the Ebola virus.

The first symptoms are similar to those of other infectious diseases like malaria, and include headache and muscle pains, high fever, nausea, vomiting and diarrhoea. Haemorrhaging begins between five and seven days after the onset of symptoms, and primarily affects the gastrointestinal tract and lungs.

Although the fatality rate for the disease is generally estimated at 75 to 80 percent, the disease has killed almost everyone infected with it so far in Angola.

Despite this bleak panorama, Angolan Health Minister Sebastiao Veloso said Wednesday in a meeting with the foreign diplomatic corps in Luanda that there is no need to impose a quarantine on Uige or to close the province's border with the Democratic Republic of Congo. (END/2005)