A new report on Iran's nuclear programme provides substantial evidence that Iran carried out extensive research into how to make a nuclear weapon prior to 2003 but is shaky about how much work has continued.
Washington's failure to gain Iraqi approval for a significant U.S. military presence in that country beyond December could make it harder for Afghanistan to agree to a similar deployment beyond 2014.
The United States and North Korea are resuming the joint search for U.S. soldiers still missing from the Korean War, one of the few positive areas of interaction between two countries estranged for more than 60 years.
U.S. presidents seeking a second term are not known for taking risks in foreign policy in election years.
U.S. Justice Department charges that elements of Iran's government were behind a foiled plot on the life of Saudi Arabia's U.S. ambassador have boggled the minds of many Americans knowledgeable about both Iran and terrorism.
As Iran continues a slow march toward potential nuclear weapons capability, diplomatic action to contain the programme is likely to shift to the International Atomic Energy Agency (IAEA), whose director general, Yukiya Amano, has taken a harder line than his predecessor about alleged military research by Iran's nuclear scientists.
In a development that could help resolve an eight-year-old diplomatic and humanitarian standoff, the Mujaheddin-e Khalq (MEK), an Iranian opposition group that has several thousand adherents at a military camp in Iraq, has agreed to allow residents to apply for refugee status and be interviewed individually by U.N. officials.
Iranian President Mahmoud Ahmadinejad said Thursday that Iran would be willing to halt production of enriched uranium that is close to weapons grade if the United States sells Iran fuel for a reactor that produces medical isotopes.
The Palestinian drive for statehood status at the United Nations injects new uncertainty into an already volatile Middle East, threatening to further isolate Israel and diminish already dwindling U.S. influence in the region.
Of all the mistakes and missed opportunities that have characterised U.S. foreign policy since Sep. 11, 2001, few may have been as consequential as the failure to improve relations with Iran.
U.S.-led efforts to build Afghan security forces capable of preventing Taliban resurgence face a series of challenges, from the reluctance of southern Pashtuns to serve in a national army, to maintaining the billions of dollars in infrastructure and equipment provided by the U.S. and other foreign countries over the past decade.
A new Congressional push to sanction Iran's Central Bank is aimed at reducing Iranian oil revenues, but could backfire and hurt the global economy.
Iran and the United States don't agree on much these days, but there are a few views they hold in common.
Iranian leaders have tried to portray democracy movements in the Arab world as inspired by their 1979 Islamic revolution and predicted that Iran's regional support would grow as pro- Western dictators fell.
U.S. hopes to withdraw forces and leave behind a stable Afghanistan may rest on whether Pakistan and India can lower bilateral tensions and refrain from using Afghan territory for a new proxy war.