Neglected tropical diseases (NTDs) are a diverse group of 21 infectious diseases that affect 1.65 billion people around the world and can disable, disfigure, and be fatal. Credit: Shutterstock.

By Thoko Elphick-Pooley
HOVE, United Kingdom, Aug 14 2024 (IPS)

Over the last ten years, I have been privileged to witness incredible progress in the fight against neglected tropical diseases (NTDs) – a journey marked by unwavering dedication, resilience, and hope.

This group of twenty-one diseases affects 1.65 billion people around the world and can disable, disfigure, and be fatal. But despite significant global obstacles, including the COVID-19 pandemic, supply chain disruptions due to the conflict in Russia and the Ukraine, and severe weather events, our collective efforts fighting NTDs have transformed the lives of millions.

As I step down from my role as Executive Director of Uniting to Combat NTDs, I am filled with a profound sense of pride and reflection. From the inclusion of NTDs in the health-related Sustainable Development Goals to the endorsement by Heads of States of the Continental Framework on NTDs and the Common Africa Position, important global and regional frameworks now exist to guide collective action and efforts.

Supporting countries on the pathway to eliminating NTDs by 2030 and helping 49 additional countries achieve elimination goals will be a smart investment for IDA21, delivering tangible and far-reaching impact

From global leaders endorsing the historic Kigali Declaration on NTDs alongside the 26th CHOGM Summit in 2022 to the Reaching the Last Mile Forum held at the 28th United Nations Climate Change Summit in 2023, we have witnessed countries standing shoulder to shoulder with donors, companies, organisations and civil society to pledge commitments to end NTDs.

These concrete actions have illuminated a path toward a future where NTDs no longer wreak havoc on the lives of vulnerable communities around the world.

The impact we have seen is real and substantial. Fifty-one countries have now eliminated at least one NTD.

Sleeping sickness, for instance, has been eliminated as a public health problem in seven countries, with Chad being the latest to achieve this milestone this year. Lymphatic filariasis has been eliminated in nineteen countries, with the Lao People’s Democratic Republic becoming the most recent to eliminate the disease as a public health threat in 2023. And progress has had a ripple effect, with some countries eliminating multiple NTDs.

In 2022, Togo became the first country in the world to eliminate four NTDs (guinea worm, lymphatic filariasis, trachoma, and sleeping sickness) while Benin and Ghana have eliminated three NTDs each, leading to recognition at an ECOWAS Heads of State Summit in 2013.

Meanwhile, 843 million people received treatment for an NTD in the year 2022 alone, powered by one of the most successful private public partnerships in the history of global health, with over 17 billion treatments for NTDs donated by the pharmaceutical industry between 2012 and 2023.

These successes have been built on years of shared experiences in NTD prevention, control, and elimination efforts.

Thoko Elphick-Pooley

The human impact of this work is the most important measure of our success. Reflecting on this journey, I recall the faces of countless individuals whose lives have been touched by this work.

The children who can now attend school, the families who can now work and thrive, the communities that are no longer shackled by preventable diseases. These stories of transformation are the heartbeat of our mission and the fuel that has driven us forward.

Yet, as we celebrate these incredible milestones, we must also take stock of the critical steps needed to ensure this progress continues. We stand at a pivotal moment, where the gains we have made must be solidified and expanded.

To do so, NTD programmes are in desperate need of sustainable, long-term financing and strengthened political commitment. One critical way to respond to this need is to prioritise disease elimination as a flagship initiative for 21st replenishment of the World Bank’s International Development Association (IDA21), which provides grants and financing to the world’s poorest countries.

This includes establishing a dedicated funding stream under IDA21’s Health Track. Doing so would ensure sustained progress against these diseases and will help the World Bank achieve its mandate to alleviate poverty, boost economic growth, and improve living conditions for millions of people on a livable planet.

With only 15% of the Sustainable Development Goals on track, the urgency to demonstrate impact at scale has never been greater.

Supporting countries on the pathway to eliminating NTDs by 2030 and helping 49 additional countries achieve elimination goals will be a smart investment for IDA21, delivering tangible and far-reaching impact. This is not just a health imperative; it is a moral and economic one.

Our journey is far from over. The path ahead requires sustained political will, continued resource mobilisation, and unwavering commitment.

We have the knowledge, the tools, and the momentum. Now is the time to harness these and push forward with renewed vigor. Let it be said, decades from now, that we did not waver in our fight. Let it be said that we left the world a healthier place, free from the scourge of neglected tropical diseases.

Thoko Elphick-Pooley is the outgoing Executive Director of Uniting to Combat Neglected Tropical Diseases.

Excerpt:

Over 600 million people in Africa require treatment for an NTD, making up 35% of the global burden. Credit: Uniting to Combat NTDs

By Thoko Elphick-Pooley
HOVE, United Kingdom, Jun 11 2021 (IPS)

As world leaders come together in the UK for the G7, the global response to COVID-19 and how we can build a better defence system against infection is at the forefront of discussions.  Whilst we applaud the incredible global efforts in tackling COVID-19 and support calls for vaccines to be shared equitably across the world, we also urge G7 leaders not to abandon efforts to tackle existing epidemics such as neglected tropical diseases (NTDs), HIV/AIDs, malaria, TB and polio.

The gains that have been made fighting these diseases must not be lost or we risk disease resurgence that will be even more costly to address, which could lead to a disastrous disease epidemic with mass consequences.

Diseases like blinding trachoma, leprosy, intestinal worms, Guinea worm disease and elephantiasis; they blind, disable, and can even be fatal. These diseases are preventable and treatable, yet they still affect 1.7 billion people around the world

As demonstrated by COVID-19, health crises don’t pop up overnight. They are a consequence of systemic underinvestment in global health, lack of strong disease surveillance systems capable of detecting disease outbreaks, global data sharing protocols, weak health systems compounded by a lack of pandemic preparedness backed by sustainable financing for global health.

COVID-19 has shown us that it doesn’t matter whether you are a low, medium or high-income country. If you lack the essential medical supplies, lives will be lost. If you have a critical gap in health workforce and infrastructure, other essential health services will suffer as resources get diverted to fighting a pandemic. Moreover, diseases do not respect borders.

This is why we must not abandon efforts to tackle existing epidemics. Take neglected tropical diseases (NTDs), for instance, coined as such because of persistent neglect. NTDs is the collective name for a group of 20 infectious diseases and conditions. Diseases like blinding trachoma, leprosy, intestinal worms, Guinea worm disease and elephantiasis. They blind, disable, and can even be fatal. These diseases are preventable and treatable, yet they still affect 1.7 billion people around the world. They are a chronic epidemic that rarely make it to the top of anyone’s agenda. They affect the most vulnerable communities in low-resource settings, primarily in Africa. 

Over 600 million people in Africa require treatment for an NTD, making up 35% of the global burden. Across the continent, 12 countries are on track to eliminate an NTD in the next three years – an extraordinary feat based on years of necessary action.

Vulnerable African communities currently face a triple burden; the pandemic has had a devastating impact on health services; cuts to NTD treatments will make them more vulnerable to tropical diseases, and the prospect of these individuals receiving a COVID-19 vaccine before 2023 is highly unlikely. This triple threat makes some communities in Africa more vulnerable to future outbreaks and increases the risk of disease resurgence, undermining efforts to improve global health security. 

It is in the interest of all the G7 countries to sustain investments that directly underpin our safety, security and economic success – and to help shape a recovery plan that promotes the health and prosperity of individuals globally. Only then will we be able to prepare for and tackle future outbreaks of deadly infections.

We welcome the focus of world leaders on One Health, which is a collaborative effort to achieve health for people, animals and the environment at the local, national and global level. We urge G7 leaders to go a step further, beyond focusing on zoonotic diseases and antimicrobial resistance, which simply isn’t enough to truly build pandemic preparedness.

Future health threats could develop from different origins, patterns, nature or impact. All aspects of One Health must be included if we are to improve global health security, including tackling other diseases, such as NTDs.

This will be a win-win for people and countries everywhere. Investments in NTDs have been a success story with 43 countries having eliminated at least one NTD, including 17 in Africa and 600 million people no longer requiring treatment for them. But the UK government’s recent exit from supporting NTD programmes, particularly during a pandemic, undermines years of progress and will deeply impact millions of Africans.

Now, 184 million tablets in 25 African countries are at high risk of expiring in 2021 and 2022 due to the funding cuts. By failing to place tackling NTDs and disease epidemics at the forefront of the global health security agenda, we risk our children’s lives and their future. Poverty will increase and access to education will be impacted. COVID-19 has shown the entire world how highly connected we are and now it is time for disease control to be dealt with collectively.

Thoko Elphick-Pooley is Executive Director of Uniting to Combat Neglected Tropical Diseases